Fig. 4

Fluctuating dlc expression was not synchronized in the developing forebrain of larval zebrafish. a, b Time-lapse imaging of mCherry signals and the heatmap of corrected mCherry signals in GFP cells (8*8 μm). Dashed lines delineate the cellular boundary of GFP cells. Time (minutes) was indicated. a’, b’ Line charts show the amplitude of mCherry signals in cell 10 (a’) and cell 35 (b’). a”, b” Curve diagrams show the autocorrelation results of cell 10 (a”) and cell 35 (b”). a, a’, a” Time-lapse imaging and the analyses of cell 10 in group 1. b, b’, b” Time-lapse imaging and the analyses of cell 35 in group 3. c Box and dot plots show the mean peak-to-peak interval, mean amplitude, mean square of autocorrelation coefficient, and range of autocorrelation coefficient in three groups. p values by Student’s t-test are indicated. d Line charts show the mean amplitude in each group. e The pie chart shows the composition of analyzed GFP cells