Fig. 4
- ID
- ZDB-FIG-250212-15
- Publication
- Pujol et al., 2024 - Short-term polystyrene nanoplastic exposure alters zebrafish male and female germline and reproductive outcomes, unveiling pollutant-impacted molecular pathways
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PS-NPs alter gene expression in males. (A) PCA plot including 3 individuals for each condition (control and PS-NPs exposed). (B) MAplot representation of up regulated (dark pink) and down regulated (turquoise) genes in PS-NPs exposed individuals (fold-change≥1; FDR<0.1). (C) Heat map showing the expression fold change as log2 for all 500 most differentially expressed genes between control and PS-NPs exposed adult zebrafish testicles. (D) Gene Ontology (GO) analysis of all up and down regulated genes showed in panel B. The number of genes assigned to each GO category is represented by the bubble size, whereas the color of the bubbles indicates its FDR. (E) Percentage of differentially expressed genes (DEGs) RNA biotype category, including antisense, long non-coding RNA, coding mRNA, pseudogenes, rRNA and small non-coding RNA. (F) Reactome pathway analysis of all dysregulated genes showed in panel B. The number of genes assigned to each pathway category is represented by the bubble size, whereas the color of the bubbles indicates its FDR. |
Reprinted from Journal of hazardous materials, 481, Pujol, G., Marín-Gual, L., González-Rodelas, L., Álvarez-González, L., Chauvigné, F., Cerdà, J., Teles, M., Roher, N., Ruiz-Herrera, A., Short-term polystyrene nanoplastic exposure alters zebrafish male and female germline and reproductive outcomes, unveiling pollutant-impacted molecular pathways, 136529136529, Copyright (2024) with permission from Elsevier. Full text @ J. Hazard. Mater.