FIGURE

Fig. 2

ID

ZDB-FIG-240808-26

Publication

Xia et al., 2024 - A Novel Role for the Longevity-Associated Protein SLC39A11 as a Manganese Transporter

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Fig. 2

Skeletal muscle mass and locomotion are reduced in slc39a11 Mut zebrafish. (A and B) H&E-stained muscle fibers in the tails of male (A) and female (B) WT and Mut zebrafish. (C to F) Gaussian distribution analysis of the area of individual muscle fibers in male (C and D) and female (E and F) zebrafish. Note that the curves shown in (D) and (E) are reproduced from (C) and (E), respectively, for comparison purposes only. (G and H) Summary of the total number (G) and total cross-sectional area (H) of muscle fibers in adult male and female WT and Mut zebrafish. (I and J) Summary of swimming speed (I) and distance traveled (J) by male and female WT and Mut zebrafish at 4, 8, and 22 months of age. (K) Diagram depicting the process for recording zebrafish swimming behavior (see Materials and Methods for details). (L) Representative images of each animal’s cumulative position in the tank tracked for 8 min, measured for 22-month-old male and female WT and Mut zebrafish. **P < 0.01, ***P < 0.001, ****P < 0.0001; ns, not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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