FIGURE

Fig. 3

ID

ZDB-FIG-240725-30

Publication

Li et al., 2024 - Biosynthetic deficiency of docosahexaenoic acid causes nonalcoholic fatty liver disease and ferroptosis-mediated hepatocyte injury

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

The function of mitochondria was impaired in the elovl2?/? hepatocyte. A, mitochondria ultrastructure in the hepatocytes of WT and ?/?. m: mitochondria. Scale bar: 200 nm. B and C, flow cytometric analysis of mitochondrial transmembrane potential after staining with JC-1 and statistical analysis of the PE/FITC fluorescence ratios. D, analysis of ATP production in WT and ?/? livers. E, heatmap of genes related with multiheteromeric enzyme complexes of oxidative phosphorylation in WT and ?/? livers. F?I, qRT-PCR analysis of genes related with multiheteromeric enzyme complexes of oxidative phosphorylation in WT and ?/? livers. N = 3 replicates. All values are mean � SD. A Student t test was used. ?p < 0.05, ??p < 0.01, ???p < 0.001. Individual p values are listed in Table S5 . ?/?, elovl2?/?; WT, wildtype.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biol. Chem.