FIGURE

Fig. 1

ID

ZDB-FIG-240725-28

Publication

Li et al., 2024 - Biosynthetic deficiency of docosahexaenoic acid causes nonalcoholic fatty liver disease and ferroptosis-mediated hepatocyte injury

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Fig. 1

Deficiency of elovl2 led to NAFLD of zebrafish. A, qRT-PCR analysis of elovl2 in different tissues. B, in situ hybridization of elovl2 on sections of WT and ?/? livers. Scale bar: 50 ?m. C, HE (hematoxylin-eosin) staining of WT and ?/? liver sections. Scale bar: 50 ?m. D, TEM (transmission electron microscopy) analysis of WT and ?/? liver sections. Scale bar: 5 ?m. E, Oil-Red staining of WT and ?/? liver sections. Scale bar: 50 ?m. F, quantitative analysis of Oil-Red staining signals. G, triglyceride (TG) content in WT and ?/? livers. All values are mean ± SD. A Student t test was used. ?p < 0.05, ??p < 0.01, ???p < 0.001. Individual p values are listed in Table S3 . ?/?, elovl2?/?; WT, wildtype.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biol. Chem.