FIGURE

Fig. 1

ID

ZDB-FIG-240703-103

Publication

Liu et al., 2024 - Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development -A Subtype of Craniovertebral Junction Malformation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Body length, body axis and survival rate of best1 zebrafish morphants. (A–F) Gross morphology of transgenic (HuC:EGFP) zebrafish embryos at 2-dpf. Compared with control morpholino (MO), knock down best1 causes shorter body length (C–F), curved body axis (C–F). (G) A time-course plot of percent survival in control versus best1 morphants for 3 days. (H) The percentage of embryos with development defects. (I, J) Quantification of body length (I) and curvature angles (J) of embryos. Columns, mean; standard error of the mean (n = 10; analysis of variance), ***p < 0.0001. Scale bar, 100 μm. dpf, days post fertilization.

Expression Data

Gene:	EGFP
Fish:	knu3Tg (AB) knu3Tg + MO1-best1 (AB) knu3Tg + MO2-best1 (AB)
Knockdown Reagents:	MO1-best1 MO2-best1
Anatomical Term:	central nervous system
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	knu3Tg + MO1-best1 (AB) knu3Tg + MO2-best1 (AB)
Knockdown Reagents:	MO1-best1 MO2-best1
Observed In:	post-vent region whole organism
Stage Range:	Shield to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neurospine