FIGURE
Fig. 6
- ID
- ZDB-FIG-240509-51
- Publication
- Arora et al., 2022 - Hypoxia-induced miR-210-3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2-mediated monocyte infiltration
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 6
Model representing miR‐210‐3p as a potential therapeutic target for lung adenocarcinoma. Left panel: LUAD solid tumor exhibits hypoxia‐associated stabilization of HIF‐1A, which by promoting miR‐210‐3p level directly involved in downregulation of CCL2 and macrophage infiltration and also favors macrophage TAM phenotype supporting tumor progression. Right panel: Therapeutic intervention of anti‐miR210‐3p LNA augment CCL2 mediated monocyte infiltration and skewing towards macrophage antitumoral M1 phenotype leading to tumor regression. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Mol. Oncol.