RB1 was altered in patients with neurodegenerative disease. ARB1 mutation rates by DNA sequence data in blood samples from PD (n = 189), AD (n = 33), HD (n = 69), and ALS (n = 75) patients from the Guangzhou KingMed Diagnostics Group Co. B Detailed information of the six mutation sites in neurodegenerative patients. C The detailed frequencies of the six mutation sites in neurodegenerative patients, normal Eastern Asian population, and frequency in the ALAF project from NCBI. PD Parkinson’s disease, AD Alzheimer’s disease, HD Huntington’s disease, ALS amyotrophic lateral sclerosis; -: no data. (Fisher’s exact test; ***P < 0.001).
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