FIGURE

Figure 4

ID

ZDB-FIG-240331-60

Publication

Stoyek et al., 2024 - POPDC1 Variants Cause Atrioventricular Node Dysfunction and Arrhythmogenic Changes in Cardiac Electrophysiology and Intracellular Calcium Handling in Zebrafish

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Figure 4

Effects of popdc1 dysfunction on V_m dynamics in larval zebrafish. Atrial (left column) and ventricular (right column) AP upstroke speed (upper row) and APD₈₀ (lower row) in WT (n = 69, N = 4), popdc1^S191F (S191F), and popdc1^KO (KO) zebrafish larvae with no morphological phenotype (n = 69 and n = 59, N = 4) or a moderate phenotype (n = 50 and n = 50, N = 5). Groups were compared by the non-parametric Kruskal–Wallis test, with Dunn’s corrected post hoc tests for multiple comparisons. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genes (Basel)