FIGURE

FIGURE 1

ID

ZDB-FIG-240327-1

Publication

Angom et al., 2024 - Forward genetic screen using a gene-breaking trap approach identifies a novel role of grin2bb-associated RNA transcript (grin2bbART) in zebrafish heart function

Other Figures

(all 9)

All Figure Page

Back to All Figure Page

FIGURE 1

Heartbeat rate analysis and phenotypic characterization of bigheart mutant. (A) Heartbeat rate analysis in wild type (bh^+/+) and bigheart mutant fish (bh^−/−) fish. X-axis represents time in days, and Y-axis represents heartbeat per minute. (B–O) Phenotypic characterization of bigheart mutant. (B–D) represent bright field images of 3 dpf wild type (WT) embryos, heterozygous embryos (bh^+/−), and bigheart homozygous (bh^−/−) mutant embryos, respectively. (E–G) represent respective fluorescence images at 3 dpf. (Images were captured at ×2.5). Yellow arrowheads indicate GFP expression in the eye and red arrowheads indicate location of the heart. (H,J,L,N) represent WT fish at 3 dpf, 15 dpf, 90 dpf and 9 months. (I,K,M,O) represent corresponding images of the bh^−/− fish at 3 dpf, 15 dpf, 90 dpf, and 9 months, respectively (***, p < 0.001, ****, p < 0.0001). The bars indicate the average values ± SD.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol