FIGURE

Fig. 6

ID

ZDB-FIG-240319-29

Publication

Megerson et al., 2023 - Kremen1 regulates the regenerative capacity of support cells and mechanosensory hair cells in the zebrafish lateral line

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Fig. 6

Dorsoventral support cells are increased in krm1nl10 mutant NMs (A and B) RNA in situ hybridization showing sost expression in dorsoventral cells in heterozygous sibling and krm1nl10 NMs at 5dpf. (C–D″) Confocal projections of Tg(myosin6b:GFP)w186 labeled hair cells (green) and Tg(sost:nlsEos)w215 labeled dorsoventral support cells (magenta) immediately following photoconversion in live 5dpf heterozygous sibling and krm1nl10 mutant NMs. (E–F) Quantification of Tg(myosin6b:GFP)w186 hair cells and total Tg(sost:nlsEos)w215 expressing NM cells. Heterozygous siblings n = 34 NM (8 fish) and krm1nl10 n = 46 NM (9 fish). All data presented as mean ± SD, Mann-Whitney test. Scale bar = 20 μm. See also Figure S2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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