FIGURE
Fig. 1
- ID
- ZDB-FIG-240307-11
- Publication
- Russell et al., 2021 - Pathogenic effect of TP73 Gene Variants in People With Amyotrophic Lateral Sclerosis
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 1
Twenty-Four Rare (ExAC NFE MAF <0.001) TP73 Nonsynonymous Variants Were Found Across Multiple Cohorts (A) TA-p73 and ?N-p73, which have opposing tumor suppressive/oncogenic functions, are expressed from 2 separate promoters. Alternative splicing events also give rise to a multitude of different isoforms (such as ?N-p73? and ?N-p73?). (B) Primary structure of TA-p73? and ?N-p73?. Number within the circles refers to the variant number in table 1. ExAC = Exome Aggregation Consortium; MAF = minor allele frequency; NFE = non-Finnish European. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Neurology