FIGURE

Figure 5

ID

ZDB-FIG-240219-36

Publication

Zapilko et al., 2023 - Generation of a Zebrafish Knock-In Model Recapitulating Childhood ETV6::RUNX1-Positive B-Cell Precursor Acute Lymphoblastic Leukemia

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Figure 5

Heatmap visualization of the significantly differentially expressed B and T lineage-associated genes between the B-ALL and E::R;pax5mut versus T-ALL zebrafish transcriptomes and their expression across the different zebrafish leukemia types (adjusted p-value ≤ 0.05). B-ALL and E::R;pax5mut zebrafish leukemias expressed several B-lineage-associated genes at significantly higher levels compared to zebrafish with T-ALL, while the expression difference was the opposite for multiple T lineage-associated genes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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