FIGURE

Figure 3

ID

ZDB-FIG-240212-77

Publication

Ruan et al., 2024 - Estrogen Signaling Inhibits the Expression of anti-Müllerian hormone (amh) and gonadal-soma-derived factor (gsdf) during the Critical Time of Sexual Fate Determination in Zebrafish

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Figure 3

The transcriptome results could be validated with qPCR, but downregulated amh and gsdf were observed in cyp17a1−/− fish after estradiol treatment from 16 to 23 dpf. (A,B) Relative expression of amh and gsdf in cyp17a1+/+ and cyp17a1−/− fish of PGC-rich and PGC-less groups at 23 dpf with qPCR. Upregulated expression of amh and gsdf was observed in cyp17a1−/− fish of PGC-rich and PGC-less groups at 23 dpf. (C,D) Relative expression of amh and gsdf in cyp17a1+/+ and cyp17a1−/− fish of PGC-rich and PGC-less groups treated with estradiol from 16 to 23 dpf. E2, 17 β-estradiol. Different letters in the bar charts represent significant differences.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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