FIGURE

Figure 2.

ID

ZDB-FIG-240206-48

Publication

Wright et al., 2024 - Zebrafish tsc1 and cxcl12a increase susceptibility to mycobacterial infection

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Figure 2.

Expression of potential miR-126 mRNA targets is conserved in zebrafish M. marinum infection.

(A) Expression of cxcr4a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (B) Expression of cxcr4b at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (C) Expression of cxcl12a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (D) Expression of tsc1a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (E) Expression of cxcr4a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (F) Expression of cxcr4b at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (G) Expression of cxcl12a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. (H) Expression of tsc1a at 1 dpi in miR-126 knockdown measured by RT-qPCR relative to uninfected scramble control embryos. Data information: each data point represents a single measurement of 10 pooled embryos and two technical replicates, with the mean and SEM shown and comparisons calculated by one-way ANOVA.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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