FIGURE

Fig. 5

ID

ZDB-FIG-240130-52

Publication

Kozol et al., 2023 - Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models

Other Figures

(all 7)

All Figure Page

Back to All Figure Page

Fig. 5

CBZ does not impact lights-off reactivity or activity in wildtype and shank3ab mutants. a) Activity during the first 30 seconds of lights-off of larvae exposed to 200 ?M CBZ. b) Activity during the full 5 minutes lights-off of larvae exposed to 200 ?M CBZ. Box plots represent 25th and 75th percentile, and median, with min to max whiskers. Sample Sizes, WT = 35, WT + CBZ = 37, shank3ab N = 24, shank3ab N + CBZ = 19, shank3ab C = 27, and shank3ab C + CBZ = 34. p values; * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	shank3a^{umi101/umi101}; shank3b^{umi102/umi102} (AB/TL) shank3a^{zf3839/zf3839}; shank3b^{zf3840/zf3840} (AB/TL)
Conditions:	chemical treatment by environment: carbamazepine lighting conditions
Observed In:	swimming behavior visual behavior
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ F1000Res