FIGURE

FIGURE 3

ID

ZDB-FIG-240124-41

Publication

Ramli et al., 2024 - Piezo1 mutant zebrafish as a model of idiopathic scoliosis

Other Figures

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FIGURE 3

Phenotype of piezo1 in-frame mutant (piezo1^{11aa del/11aa del}). (A) Time course observation of mineralized bone using alizarin red S staining between wildtype and piezo1^{11aa del/11aa del} mutant from larvae (8 dpf) to young adult (35 dpf) (Used scale 500 μm) and 3D rendering of micro-CT images of wildtype and piezo1^{11aa del/11aa del} mutant at 4 months. (B) Graph depicting body length. (C) Average of total Cobb angle. Cobb angles were measured according to previous study (Bearce et al., 2022). Values are presented as mean ± SD and analyzed using Student’s t-test. ****p < 0.0001. ns means non-significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	piezo1^{ou2048/ou2048}
Observed In:	vertebral column vertebral column bone tissue whole organism
Stage Range:	Days 14-20 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet