FIGURE

Fig. 1

ID

ZDB-FIG-240111-9

Publication

Tan et al., 2023 - Fgf, Hh, and pax2a differentially regulate expression of pax5 and pou3f3b in vestibular and auditory maculae in the zebrafish otic vesicle

Other Figures

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Fig. 1

Effects of disrupting Fgf, Hh or early sensory development. Dorsolateral views of pax5 (A-F) and pou3f3b (G-L) at 24 hpf under conditions listed at the top. (A-D, G-J) Drug treatments were administered at 12 hpf to inhibit Fgf (70 μM SU5402) or Hh (150 μM SANT-1). The same treatment conditions were used in subsequent figures unless otherwise noted. (E, K) atoh1a-MO and atoh1b-MO were co-injected at the one-cell stage. (F, L) expression in pax2a−/− mutants. (M, N) Live images showing brn3c:Gfp expression in hair cells at 30 hpf in a wild-type embryo (M) and an atoh1a-atoh1b double morphant (N). Oval marquees denote the outer edge of the otic vesicle in this and all subsequent figures.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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