FIGURE

Fig. 2

ID

ZDB-FIG-231228-151

Publication

Rebello et al., 2023 - COL11A2 as a candidate gene for vertebral malformations and congenital scoliosis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Vertebral fusion in all col11a2 genotypes is biased to the caudal end of the spine. Heatmaps indicating the position of vertebral fusions along the length of the spine, across col11a2 genotypes. Each row of the heatmap represents an individual animal at 21dpf, with colored blocks indicating the positions of fused vertebrae. Graph depicts fusion penetrance between all genotypes, and demonstrates that col11a2del/+ fish have significantly more fusions than wildtype, indicating haploinsufficiency. Significance was calculated by chi-square analysis and error bars represent 95% confidence interval. wt: wild type. ns?not significant, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.