FIGURE

Figure 5

ID

ZDB-FIG-231225-113

Publication

Zhai et al., 2023 - IL-6 Mutation Attenuates Liver Injury Caused by Aeromonas hydrophila Infection by Reducing Oxidative Stress in Zebrafish

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Figure 5

Effect of il-6 mutation on oxidative stress triggered by A. hydrophila infection. (A) MDA and (B) SOD levels in liver tissues. Samples used for enzyme activity (biological replicates = 5, experimental repetitions = 3) were collected 12 h after A. hydrophila infection. Data were subjected to the Student’s t-test to identify the significance. ** p < 0.01. (C) Representative staining of ROS in liver sections. Samples were collected at 12 h after A. hydrophila infection. Frozen tissue sections were used for immunofluorescence detection of ROS. Red fluorescence corresponds to the presence of ROS, while blue fluorescence represents the cell nucleus. Scale bar = 50 μm. WT-AH: WT zebrafish treated with A. hydrophila; KO-AH: il-6^−/− zebrafish treated with A. hydrophila.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB il6^{zf4118/zf4118} (AB)
Condition:	bacterial treatment by injection: Aeromonas hydrophila
Observed In:	liver malonaldehyde liver reactive oxygen species liver superoxide dismutase activity
Stage:	Adult

Phenotype Detail

Acknowledgments

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