FIGURE

Figure 2

ID

ZDB-FIG-231225-110

Publication

Zhai et al., 2023 - IL-6 Mutation Attenuates Liver Injury Caused by Aeromonas hydrophila Infection by Reducing Oxidative Stress in Zebrafish

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Figure 2

Liver injury in WT and il-6^−/− zebrafish post A. hydrophila infection. (A) Pathological changes in WT and il-6^−/− zebrafish liver tissue after A. hydrophila infection were indicated by Hematoxylin and Eosin (HE) staining. Samples were collected at 12 h after A. hydrophila infection. The black arrow indicates infiltration of red blood cells. Scale bar = 50 μm. il-6^−/− zebrafish had milder liver injury compared to WT zebrafish after A. hydrophila infection. (B) Liver alanine transaminase (ALT) and aspartate transaminase (AST) levels. Samples used for enzyme activity (biological replicates = 5, experimental repetitions = 3) were collected 12 h after A. hydrophila infection. Data were subjected to the Student’s t-test to identify the significance. The levels of AST and ALT in the liver of il-6^−/− zebrafish were significantly lower than those of WT zebrafish. ** p < 0.01. WT-AH: WT zebrafish treated with A. hydrophila; KO-AH: il-6^−/− zebrafish treated with A. hydrophila.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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