FIGURE

Figure 3

ID

ZDB-FIG-230916-154

Publication

Omar et al., 2023 - Parkinson's disease model in zebrafish using intraperitoneal MPTP injection

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Figure 3

The relative gene expression in the zebrafish model across the group. th1 gene was significantly down-regulated in MPTP1.3, MPTP1.5, MPTP2.1, and MPTP2.3. th2 gene expression was down-regulated initially however was not statistically significant. However, at MPTP1.10, there is a spike in th2 gene expression which eventually down-regulated in MPTP1.30. dat gene was down-regulated, especially in MPTP1.3 and MPTP2.3 then steadily increased afterward; however, these changes were not statistically significant. (A) The relative gene expression between one- and two-time injections. (B) The relative gene expression among MPTP days 1 to 30. Data are presented as mean ± SEM. Asterisks (*) indicate a significant difference between vehicle and treated fish at *p < 0.01 or **p < 0.05.

Expression Data

Gene:	th
Fish:	WT
Condition:	chemical treatment by injection: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Anatomical Term:	brain
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by injection: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Observed In:	brain
Stage:	Adult

Phenotype Detail

Acknowledgments

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