FIGURE

Figure 1

ID

ZDB-FIG-230916-113

Publication

Dalle Carbonare et al., 2023 - Modulation of miR-146b Expression during Aging and the Impact of Physical Activity on Its Expression and Chondrogenic Progenitors

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Figure 1

MiR-146b expression during differentiation. MiR-146b expression is higher in MSCs committed to adipogenic lineage compared to chondrogenic or osteogenic lineage (miR-146b expression in chondrogenic or osteogenic groups compared to adipogenic group) (A). MiR-146b expression is poorly modulated during adipogenesis (miR-146b expression at 7 or 14 days of differentiation compared to 3 days of differentiation) (B) and highly modulated during chondrogenic (C) or osteogenic (D) differentiation. Forced expression of miR-146b induced the upregulation of PPARG2 and the downregulation of SOX9 (E). Data are shown as mean ± standard deviation (SD); * p < 0.05; ** p < 0.01; *** p < 0.005. For each experiment, six independent analyses were performed. In figure (B–D), miR-146b expression at 7 or 14 days of differentiation is compared to that at 3 days of differentiation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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