FIGURE

Fig. 4

ID

ZDB-FIG-230823-38

Publication

Yang et al., 2022 - Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (ehhadh) is essential for production of DHA in zebrafish

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Fig. 4

The mRNA expression levels of fatty acid metabolism-related genes in liver of WT and Ehhadh transgenic zebrafish (Tg:Ehhadh). A: Effects of Ehhadh overexpression on mRNA expression of PUFA synthesis-related genes in liver. B: Effects of Ehhadh overexpression on mRNA expression of Peroxisome β-oxidation related genes in liver. C: Effects of Ehhadh overexpression on mRNA expression of pparα and srebf1 in liver. D: The effect of Ehhadh overexpression on DHA synthesis pathway. The blue arrow indicates the downward adjustment, and the red arrow indicates the upward adjustment. ns means no significant difference; ∗ means P < 0.05; ∗∗ means P < 0.01; ∗∗∗ means P < 0.001. acaa1, acetyl-CoA acyltransferase 1; acaa2, acetyl-CoA acyltransferase 2; acox1, acyl-CoA oxidase 1; acox3, acyl-CoA oxidase 1; Ehhadh, enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase; elovl2, fatty acid elongase 2; elovl4a, fatty acid elongase 4a; elovl4b, fatty acid elongase 4b; elovl5, fatty acid elongase 5; fads2, fatty acid desaturase 2; hsd17b4, hydroxysteroid 17-beta dehydrogenase 4; pparαa, peroxisome proliferator activated receptor alpha a; pparαb, peroxisome proliferator activated receptor alpha b; srebf1, sterol regulatory element binding transcription factor 1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Lipid Res.