FIGURE

Figure 4.

ID

ZDB-FIG-230719-13

Publication

Dryer et al., 2023 - Comparison of tumor growth assessment using GFP fluorescence and DiI labeling in a zebrafish xenograft model

Other Figures

All Figure Page

Back to All Figure Page

Figure 4.

Comparison of GFP fluorescence and DiI labeling of zebrafish xenografts of GFP-expressing and DiI labeled MDA-MB-231 cells. (a) Representative DiI, GFP and merged fluorescence images of a zebrafish xenograft tumor on Day 0 and Day 3 post-injection into 2pdf zebrafish embryos, as indicated. The white arrow indicates the DiI labeled border area of the tumor that lacks GFP-fluorescence. Scale bar = 50 μm. (b) Percent change in the tumor area and intensity determined based on the GFP fluorescence or DiI labeling. Average percent change in tumor area was 34.62 ± 7.2 based on the GFP fluorescence and 52.22 ± 7.86 based on the DiI labeling (n = 37). Average percent change in tumor intensity was 9.45 ± 5.89 based on the GFP fluorescence and 35.08 ± 6.75 based on the DiI labeling (n = 37). *P < .05, paired-samples Student’s T-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cancer Biol. Ther.