ZFIN Image: Dryer et al., 2023, Figure 4.

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Figure Caption

Figure 4.

Comparison of GFP fluorescence and DiI labeling of zebrafish xenografts of GFP-expressing and DiI labeled MDA-MB-231 cells. (a) Representative DiI, GFP and merged fluorescence images of a zebrafish xenograft tumor on Day 0 and Day 3 post-injection into 2pdf zebrafish embryos, as indicated. The white arrow indicates the DiI labeled border area of the tumor that lacks GFP-fluorescence. Scale bar = 50 μm. (b) Percent change in the tumor area and intensity determined based on the GFP fluorescence or DiI labeling. Average percent change in tumor area was 34.62 ± 7.2 based on the GFP fluorescence and 52.22 ± 7.86 based on the DiI labeling (n = 37). Average percent change in tumor intensity was 9.45 ± 5.89 based on the GFP fluorescence and 35.08 ± 6.75 based on the DiI labeling (n = 37). *P < .05, paired-samples Student’s T-test.

Acknowledgments

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