FIGURE

Figure 6

ID

ZDB-FIG-230518-9

Publication

McConnell et al., 2023 - Immune gene variation associated with chromosome-scale differences among individual zebrafish genomes

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Figure 6

MHC and NLR genes associated with zero coverage regions (ZCRs). The percentage of (A) major histocompatibility complex (MHC) genes, (B) NOD-like receptor (NLR) genes, or (C) all genes in each of three human or zebrafish genomes, with at least one exon overlapping ZCRs. ‘Comb.’ refers to the combined list of genes from all three individuals that overlaps with ZCRs. CHM, CEU, and YRI are human samples from the 1000 Genomes Project representing: a haploid complete hydatidiform mole, CHM1; Utah Resident (CEPH) with European Ancestry, NA12878; Yoruba in Ibadan, Nigeria, 19240; respectively. CG2 and CG1 are clonal zebrafish lines, and AB3 is a partially inbred fish, all on the AB genetic background (the gene lists used for (A,B) are found in Table ^S9. Total number of zebrafish MHC genes = 42; total number of human MHC genes = 37. Total number of zebrafish NLR genes = 368^⁹. The data used to make the bar graphs are found in Table ^S11).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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