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Fig. 2

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ZDB-FIG-230410-2

Publication

Kourpa et al., 2022 - 15-keto-Prostaglandin E₂ exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors

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Fig. 2

Fig. 2. Prostaglandin lipidomic profiles of developing zebrafish embryos. (a-h) Lipidomic analysis of whole zebrafish embryos at two different developmental stages (48 hpf and 120 hpf) showing the levels of the main prostaglandins and their metabolites: (a) PGE₂ (P = 0.0002), (b) 15-keto-PGE₂ (P = 0.0018), (c) 13,14-dihydro-15-keto-PGE₂ (P = 0.0008), (d) PGF_2a (P = 0.0001), (e) 15-keto-PGF_2a (P = 0.0025), (f) 13,14-dihydro-15-keto-PGF_2a (P = 0.0028), (g) PGD₂ (P = 0.5006) and (h) 13,14-dihydro-15-keto-PGD₂ (P = 0.0175). For 48 hpf: N = 11, n = 275 (less points in some of the graphs indicate missing values due to non-detectable levels). For 120 hpf: N = 6, n = 150. For all graphs, two-tailed unpaired t-test with Welch’s correction was performed. Values are plotted as mean ± SD; P < 0.05 considered significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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