FIGURE

Fig. 3

ID

ZDB-FIG-230322-38

Publication

Tyrkalska et al., 2022 - Silica crystals activate toll-like receptors and inflammasomes to promote local and systemic immune responses in zebrafish

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Fig. 3

Fig. 3. Silica crystals promotes local and systemic inflammation in zebrafish larvae. SiO₂ crystals or PBS were injected in the hindbrain ventricle (HBV, dash line) of 2 dpf Tg(NFkB-RE:eGFP) (A-D) and Tg(il1b:eGFP) (E-H). Nfkb activation (A-D) and Il1b production (E-H) were analyzed by fluorescence microscopy from 1 to 48 hpi (A, B, E, F) or 24 hpi (C, D, G, H). Each dot represents one individual and the mean ± S.E.M. for each group is also shown. P values were calculated using one-way ANOVA and Tukey multiple range test. ns, not significant, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. Bars: 100 μm (A, E), 500 μm (C, G).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Comp. Immunol.