FIGURE

Fig. 2

ID

ZDB-FIG-230315-109

Publication

Zhang et al., 2022 - Deficiency of nde1 in zebrafish induces brain inflammatory responses and autism-like behavior

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Fig. 2

Morphological analysis and apoptosis analysis of nde1^−/−

(A) AO staining of nde1^+/+ and nde1^−/− at 30hpf; white dotted oval indicates telencephalon, midbrain, rhombomere, and spine, respectively. Scale bar: 0.2 mm.

(B) Statistics of apoptotic bodies after AO staining in nde1^+/+ and nde1^−/−.

(C) HE-stained paraffin sections of midbrain of nde1^+/+ and nde1^−/−. Black arrow indicates the gaps between the ventricles; red arrow indicates valvula cerebelli. Scale bar: 0.5 mm. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Data are represented as mean ± SEM

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nde1^{zf3784/zf3784} (TU)
Observed In:	brain midbrain apoptotic process rhombomere apoptotic process spinal cord apoptotic process telencephalon apoptotic process valvula cerebelli ventricular system (all 7)
Stage Range:	Prim-15 to Adult

Phenotype Detail

Acknowledgments

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