FIGURE

Fig. 2

ID

ZDB-FIG-230212-2

Publication

Rashid et al., 2021 - HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein

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Fig. 2

HI-NESS labels chromosomes in HeLa cells in culture (Confocal microscopy, single Z-plane). Line scans (marked in red with start and end positions indicated with S and E, respectively) across nuclei of HeLa cells co-stained with HI-NESS (green) and SiR-Hoechst (magenta) highlight the overlap between the distributions of the two DNA labels. However, HI-NESS also accumulates in nucleoli due to high levels of the protein in the nucleus and its affinity for RNA as detected in in vitro studies (Supplementary Figure S4; Supplementary Table S1).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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