FIGURE

Figure 5

ID

ZDB-FIG-230124-135

Publication

Kar et al., 2023 - Predicting Modifiers of Genotype-Phenotype Correlations in Craniofacial Development

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Figure 5

Vinblastine exacerbates the gata3 mutant phenotype. Representative flat mounts show the range of defects in DMSO treated (A–C) and vinblastine treated (D,E) embryos. Vinblastine treatment leads to a statistically significant decrease in intact trabeculae count ((F), p < 0.05), a reduction in trabeculae length ((G), p < 0.05) and an increase in trabeculae width ((H), p < 0.05). Error bars represent SEM. Trabecular width (w as shown in (A)) measurements were taken at the midpoint of each trabecula as determined from the length (l as shown in (A)) from the boundary with the ethmoid plate to the anterior edge of the prechordal plate. Scale bar = 0.5 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.