FIGURE
Figure 7—figure supplement 1.
- ID
- ZDB-FIG-230123-27
- Publication
- Sabharwal et al., 2022 - Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality
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Figure 7—figure supplement 1.
Irreversible liver-specific Cre recombinase-mediated rescue.lrpprcGBT0235/+ adult zebrafish were crossed with Tg(−2.8fabp10:Cre;−0.8cryaa:Venus)S955 to obtain double transgenic adult zebrafish expressing both the GBT cassette and the fabp10 driven Cre recombinase. Tg(fabp10:Cre)lrpprcGBT0235/GBT0235 zebrafish larvae demonstrate a loss of RFP expression in the liver contributed by the reversion of mutagenicity RFP cassette mediated via liver-specific Cre recombinase (magnification- 5×; scale bar: 200 µm). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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