Image
Figure Caption

Figure 7—figure supplement 1.

Irreversible liver-specific Cre recombinase-mediated rescue.

lrpprcGBT0235/+ adult zebrafish were crossed with Tg(−2.8fabp10:Cre;−0.8cryaa:Venus)S955 to obtain double transgenic adult zebrafish expressing both the GBT cassette and the fabp10 driven Cre recombinase. Tg(fabp10:Cre)lrpprcGBT0235/GBT0235 zebrafish larvae demonstrate a loss of RFP expression in the liver contributed by the reversion of mutagenicity RFP cassette mediated via liver-specific Cre recombinase (magnification- 5×; scale bar: 200 µm).

Acknowledgments
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