FIGURE

Fig. 1

ID

ZDB-FIG-230115-53

Publication

Leventea et al., 2021 - Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor

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Fig. 1

cep290 mutant phenotype. (A) Phenotype of homozygous cep290^sa1383 adult fish. (B) Sequence of the sa1383 mutant allele used in this study. (C) Cep290 domain structure showing mutations used in this study. (D and E) Example swimming tracks of heterozygote control (Left) and homozygous mutant (Right) larvae after osmotic shock (D) and adults (E); black represents slow movement or static, green represents medium, and red represents fast movement. (F and G) Total distance traveled for swimming trajectories (mm) such as ones shown in (D and E) for larvae after osmotic shock (F) and adults (G). ****P < 0.0001; ***P < 0.001; Student’s t test; 95% CI.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cep290^{sa1383/sa1383} cep290^sa1383/+
Condition:	water salinity
Observed In:	whole organism response to osmotic stress whole organism swimming behavior
Stage Range:	Day 5 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA