FIGURE

Fig. 7

ID

ZDB-FIG-221223-15

Publication

Qin et al., 2021 - Uptake of oxidative stress-mediated extracellular vesicles by vascular endothelial cells under low magnitude shear stress

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Fig. 7

Low magnitude shear stress-induced oxidative stress of endothelial cells was a regulator of RBCEVs uptake. (a) Model diagram of endothelial cells uptake in different shear stresses. (c) Laser confocal images of RBCEVs uptake by endothelial cells in different shear stresses. (b) and (d) Flow cytometry analysis for uptake of RBCEVs by endothelial cells in different shear stresses. (e–f) ROS production was measured by CM-H2DCFDA probe in vitro. (g–h) ROS production was measured by CM-H2DCFDA probe in vivo. (i) SOD, MDA, and MCP-1 levels were detected by an ELISA assay. (j–k) Flow cytometry analysis of RBCEVs uptake by endothelial cells treated with two antioxidants. L: lumen. (n = 5). Significance is indicated as no significance (ns), or P < 0.001 (***).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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