Fig. 8
Fig. 8. Trunk neural phenotype in cont BMP-treated (Z-stack). (A,D) A mock animals showing wild-type phenotype. (B,E) 4q+22 h continuous animals showing a severe VNC collapse phenotype. (C,F) 4q+22 h continuous animals showing a mild VNC collapse. (A–C) acetylated-tubulin showing neurotroch cilia, (A′-C′) acetylated-tubulin in the VNC. (D–F) Hoechst nuclear stain. (D′-F′) 5HT (D″-F″) Pax, arrowhead: normally bilaterally-symmetric cells on either side of the midline in each segment. Figure panels with the same letter represent the same animal. A, anterior, L, left side, nt, neurotroch; pt, prototroch; tt, telotroch; VNC, ventral nerve cord; scale bar = 50 μm (G) Boxplot showing the significant effect of treatment on proportion of segments with collapsed hemiganglia, letters indicate significance groups. |
Reprinted from Developmental Biology, 478, Webster, N.B., Corbet, M., Sur, A., Meyer, N.P., Role of BMP signaling during early development of the annelid Capitella teleta, 183-204, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.