FIGURE

Fig. 3

ID

ZDB-FIG-221119-3

Publication

Shen et al., 2022 - The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1

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Fig. 3

Knockdown of ALKBH5 inhibits the proliferation and metastasis of lung cancer cells in vivo. A, B The CM-DiI-positive signals in the yolk and trunk of zebrafish were imaged by confocal microscopy at 4 days postinjection of A549 cells transfected with si-ALKBH5 or NC. The red signals indicate the cancer cells labeled CM-DiI. The green signals indicate the blood vessels that expressed EGFP. The white arrows represent the metastatic cells. Scale bar: 100 μm. C, D Statistical analysis of the proliferation and metastasis of A549 cells after knockdown of ALKBH5. NC: n = 13, si-ALKBH5: n = 14. E, F Statistical analysis of the proliferation and metastasis of H1975 cells after knockdown of ALKBH5. NC: n = 13, si-ALKBH5: n = 14. *: P < 0.05, **: P < 0.01, ***: P < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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