FIGURE

Figure 6

ID

ZDB-FIG-221118-161

Publication

Mignani et al., 2022 - Bi-Allelic Mutations in Zebrafish pank2 Gene Lead to Testicular Atrophy and Perturbed Behavior without Signs of Neurodegeneration

Other Figures

All Figure Page

Back to All Figure Page

Figure 6

Primordial germ line and testis evaluation. (A) WISH for nanos3 in 24 hpf embryos. Size bar = 500 µm and 200 µm. (B) Quantification of nanos3 positive cells in control (Ctl) and D4 embryos (Ctl mean = 8.18 N = 83; D4 mean = 5.07 N = 85, **** p < 0.0001, Student’s t-test). (C) Representative histological sagittal sections of 1-year-old fish, stained with hematoxylin-eosin. Red circle indicates the testis. N = 5 for each group. Magnification 10× and 40×. Size bar = 2000 µm and 500 µm (D) Quantification of testis area performed on histological sections; Ctl mean = 0.92 mm²; D4 mean = 0.24 mm² ** p < 0.01, Mann–Whitney U test.

Expression Data

Gene:	nanos3
Fish:	WT pank2^ubx1/ubx1
Anatomical Term:	primordial germ cell
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pank2^ubx1/ubx1
Observed In:	primordial germ cell testis
Stage Range:	Prim-5 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.