FIGURE

FIGURE 2

ID

ZDB-FIG-221118-125

Publication

Xia et al., 2022 - COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells

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FIGURE 2

N-glycan analysis of SW1353 and HEK293T cells carrying COG4 mutations. (A) N-glycans of SW1353 COG4^p.G516R and COG4-KO cells compared to WT SW1353 cells. (B) N-glycans of HEK293T cells overexpressing WT-COG4-Myc or G516R-COG4-Myc or COG4-KO compared to control HEK293T cells. The different Golgi cisterna tags show the location of indicated glycans. Data were presented as bar graph with mean and SD. Experiments were performed in duplicate with similar results. Unpaired two-tailed t-test was used. ****, p < 0.001; ***, p < 0.005; **, p < 0.01; *, p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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