FIGURE

Fig. 6

ID

ZDB-FIG-221030-76

Publication

Han et al., 2021 - Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish

Other Figures

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Fig. 6

Confirmation of zebrafish MPNSTs with S100 and H3K27me3. Four random tumors from tp53 heterozygotes and double heterozygotes (tp53 and sa1299) were stained with S100 and H3K27me3 antibodies. (A–C, G–I, M–O, S–U): tp53 heterozygotes. (D–F, J–L, P–R, V–X): double heterozygotes. HE (hematoxylin and eosin) staining: A, D, G, J, M, P, S, V. IHC with S100 antibody: B, E, H, K, N, Q, T, W. IHC with H3K27me antibody staining: C, F, I, L, O, R, U, X. Some stained cells are non-Schwann cells in these sections, but they serve as a positive control for the antibody specificity. All the images were taken at the same magnification. Scale bar = 100 μm in panel A

Expression Data

Antibodies:	Ab1-s100 Ab8-h3
Fish:	tp53^zdf1/+ smarcad1a^sa1299/+; tp53^zdf1/+
Anatomical Term:	whole organism neurofibrosarcoma
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tp53^zdf1/+ smarcad1a^sa1299/+; tp53^zdf1/+
Observed In:	whole organism neurofibrosarcoma
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genes Chromosomes Cancer