FIGURE

Figure 2

ID

ZDB-FIG-221018-105

Publication

Charlie-Silva et al., 2022 - Plasma proteome responses in zebrafish following λ-carrageenan-Induced inflammation are mediated by PMN leukocytes and correlate highly with their human counterparts

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Figure 2

Intraperitoneal injection of λ-CGN stimulates a highly selective cellular immune response in zebrafish. (A) The time-dependent infiltrating mean number of total leukocytes in control (PBS) and λ-CGN-injected fish with two different concentrations. (B) Quantification of the progressive mean abdominal edema expansion using the highest (3.5%) λ-CGN concentration 4h after the injection. (C) Representative dot plot showing the gating used to discriminate between lymphocytes [L], neutrophils [N], and monocytes [M] present in the ascites recovered from the PBS (red) or 3.5% λ-CGN-treated (blue) fish 4h post-injection. (D–F) Quantification of data in (C) by cellular type. (Note the resulting inhibition in the monocyte fraction) (n = 21 fish per group) Results were analyzed using an unpaired t-test (p< 0.05) respective to the control value. Error bars indicate SD.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol