FIGURE

Figure 1

ID

ZDB-FIG-221018-104

Publication

Charlie-Silva et al., 2022 - Plasma proteome responses in zebrafish following λ-carrageenan-Induced inflammation are mediated by PMN leukocytes and correlate highly with their human counterparts

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Figure 1

Characterization of the λ-CGN-induced abdominal edema model of inflammation in zebrafish (Danio rerio) male adults. (A) Representative images of healthy adult zebrafish at the beginning of the trial. (Upper panel) In vivo X-ray image (Xtreme system). (Lower panel) Real-time image of live zebrafish showing the λ-CGN injection site (red asterisk). The light color represents the abdominal cavity area forming edema analyzed in this study. (B) Live immobilized λ-CGN-induced male zebrafish specimens were evaluated one by one following a side and ventral pattern using a classical optical coherence tomography (OCT) device. The representative scanning 3D reconstruction is presented on the right side. (C) Spectral domain OCT images of a healthy and inflamed fish highlighting the edema boundaries and tissue disorganization (red dotted lines) on the ventral and horizontal superficial layers 4h post-injection of PBS or 3.5% λ-CGN, respectively. Scale bar 250 µm.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol