FIGURE

Fig. 1

ID
ZDB-FIG-220905-1
Publication
Neuffer et al., 2022 - AP-3 complex delta subunit gene, ap3d1, regulates melanogenesis and melanophore survival via autophagy in zebrafish (Danio rerio)
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Fig. 1

crasher mutants have fewer and lighter melanophores. (a, a') Lateral (a) and dorsal (a’) view of crasher siblings with typical the wild-type (WT) phenotype at 3 days postfertilization (3 dpf). (b, b′) Lateral (b) and dorsal (b′) view of homozygous recessive (mutant) phenotype. Arrowheads indicate punctate melanophores. (c) Melanophore count boxplot at 3 dpf. Mutants average 25% fewer melanophores (μ = 188, SD = 20.4) than WT siblings (μ = 255, SD = 20.9). (Student's t-test, t[28] = −8.87, p = 1.27 × 10−9***). (d) Iridophore count boxplot at 3 dpf. Mutants vary more (median = 25, interquartile range [IQR] = 23 to 29.5), but have similar iridophore numbers as WT siblings (median = 28, IQR = 22–29) (Mann–Whitney U test, W = 11.05 × 101, p = 0.95). Scale bar is 1 mm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Pigment Cell Melanoma Res.