FIGURE

Fig. 3

ID

ZDB-FIG-220829-213

Publication

Quelle-Regaldie et al., 2022 - A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype

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Fig. 3

Graphic representation of expression analysis by RT-qPCR. (A) Cbln12 expression is significantly reduced in nop56^+/− and nop56^−/− embryos between at 72 and 120 hpf in comparison with wild-type embryos (p-value < 0.0001). (B) Ptf1a expression is significantly reduced in nop56^−/− embryos at 72 and 120 hpf (p-value < 0.0001.) (C) Grid2 expression is significantly reduced in nop56^+/− and nop56^−/− embryos between at 72 and 120 hpf in comparison with wild-type embryos (p-value < 0.0001). Statistically significant data in the graphs is indicated with a *.

Expression Data

Genes:	cbln12 grid2 ptf1a
Fish:	WT nop56^{sa12582/sa12582} nop56^sa12582/+
Anatomical Term:	head
Stage Range:	Protruding-mouth to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nop56^{sa12582/sa12582} nop56^sa12582/+
Observed In:	head
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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