Gene
cbln12
- ID
- ZDB-GENE-070912-11
- Name
- cerebellin 12
- Symbol
- cbln12 Nomenclature History
- Previous Names
-
- sghC1q12 (1)
- si:ch211-10e2.5
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to be involved in maintenance of synapse structure. Predicted to be active in glutamatergic synapse and synaptic cleft. Is expressed in brain and head.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la028812Tg | Transgenic insertion | Unknown | Unknown | DNA |
1 - 1 of 1
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C1q domain | Cerebellin Synaptic Organizer | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:B0R0I5 | InterPro | 199 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cbln12-201
(1)
|
Ensembl | 1,107 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(cbln12:EnvA,myl7:mCherry) |
|
| 1 | Dohaku et al., 2019 | |
| Tg(cbln12:GAL4FF) |
|
| 1 | (2) | |
| Tg(cbln12:LOXP-TagCFP-LOXP-Kaede) |
|
| 1 | (2) | |
| Tg(cbln12:Tva-mCherry) |
|
| 1 | Dohaku et al., 2019 | |
| Tg(cbln12:Venus) |
|
| 1 | Dohaku et al., 2019 |
1 - 5 of 5
Show
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-10E2 | ZFIN Curated Data |
1 - 1 of 1
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001243318 (1) | 1104 nt | ||
| Genomic | GenBank:AL928674 (1) | 205118 nt | ||
| Polypeptide | UniProtKB:B0R0I5 (1) | 199 aa |
No data available
- Itoh, T., Uehara, M., Yura, S., Wang, J.C., Fujii, Y., Nakanishi, A., Shimizu, T., Hibi, M. (2024) Foxp- and Skor-family proteins control differentiation of Purkinje cells from Ptf1a and Neurogenin1-expressing progenitors in zebrafish. Development (Cambridge, England). 151(7):
- Quelle-Regaldie, A., Folgueira, M., Yáñez, J., Sobrido-Cameán, D., Alba-González, A., Barreiro-Iglesias, A., Sobrido, M.J., Sánchez, L. (2022) A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype. Biomedicines. 10(8)
- Koyama, W., Hosomi, R., Matsuda, K., Kawakami, K., Hibi, M., Shimizu, T. (2021) Involvement of cerebellar neural circuits in active avoidance conditioning in zebrafish. eNeuro. 8(3):
- Dohaku, R., Yamaguchi, M., Yamamoto, N., Shimizu, T., Osakada, F., Hibi, M. (2019) Tracing of Afferent Connections in the Zebrafish Cerebellum Using Recombinant Rabies Virus. Frontiers in neural circuits. 13:30
- Kidwell, C.U., Su, C.Y., Hibi, M., Moens, C.B. (2018) Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum. Developmental Biology. 438(1):44-56
- Takeuchi, M., Yamaguchi, S., Sakakibara, M., Hayashi, T., Matsuda, K., Hara, Y., Tanegashima, C., Shimizu, T., Kuraku, S., Hibi, M. (2017) Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. The Journal of comparative neurology. 525(7):1558-1585
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Carland, T.M., Locke, J.B., Nizet, V., and Gerwick, L. (2012) Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Developmental and comparative immunology. 36(1):31-8
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466
1 - 10 of 10
Show