FIGURE

Fig. 2

ID

ZDB-FIG-220808-2

Publication

Ding et al., 2022 - Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome

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Fig. 2

Venn diagrams show the number of metabolites measured by HR-MAS NMR spectroscopy in response to infection in the lepb⁺ and lepb^ibl54 zebrafish larvae. A A Venn diagram shows the number of metabolites in response to M. marinum infection in the lepb⁺ and lepb^ibl54 larvae with p < 0.05. B A Venn diagram shows the number of metabolites in response to M. marinum infection in the lepb⁺ and lepb^ibl54 larvae with p < 0.05 and FC > 1.5 or FC < − 1.5. FC fold change. C Quantification of the common six metabolites in B. ****p < 0.0001. D Quantification of the one metabolite lactate in A. *p < 0.05. ns non-significant. E Quantification of the one metabolite trimethylamine N-oxide in B. **p < 0.01, ***p < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT lepb^ibl54/ibl54
Condition:	bacterial treatment by injection: Mycobacterium marinum M
Observed In:	whole organism alanine whole organism aspartate whole organism citrulline whole organism lysine whole organism phenylalanine whole organism tyrosine
Stage:	Day 5

Phenotype Detail

Acknowledgments

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