FIGURE

Fig. 7

ID

ZDB-FIG-220808-7

Publication

Ding et al., 2022 - Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome

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Fig. 7

Transcriptome signature sets of lepb^ibl54 and lepb⁺ zebrafish larvae at 5 dpi in the absence and presence of M. marinum infection. A A volcano plot of the signature set of lepb⁺ infected larvae compared to the lepb⁺ uninfected control. We used p < 0.05 and FC > 1.5 or FC < − 1.5 as cutoff values for all the figures. B A volcano plot of the signature set of lepb^ibl54 infected larvae compared to the lepb^ibl54 uninfected control. C A Venn diagram shows the number of differentially expressed genes (DEGs) in response to infection in the lepb⁺ and lepb^ibl54 larvae. D The FC and p value of the three groups of genes, shown in C, belonging to the two GO terms “response to bacterium” and “inflammatory responses”. E A volcano plot of the signature set of lepb^ibl54 compared to lepb⁺ larvae in the uninfected control situation. F A volcano plot of the signature set of lepb^ibl54 compared to lepb⁺ larvae in the infected situation. G A Venn diagram shows the number of DEGs between the lepb^ibl54 and lepb⁺ in the uninfected control and infected conditions. H The FC and p value of the three groups of genes, shown in G, belonging to the two GO terms

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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