FIGURE

Figure 3

ID

ZDB-FIG-220801-18

Publication

Gessler et al., 2022 - Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling

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Figure 3

Synergistic effects between adenosine deaminase family members. (A) Combining low concentrations of the ada splice-blocking morpholino oligonucleotide (MO) and the ada2b translation-blocking MO did not affect zebrafish embryogenesis. However, the combination significantly delayed the repair process in comparison to the control (ctrl) or either single MO. (B) Combining low concentrations of the ada2a translation-blocking MO and the ada2b translation-blocking MO did not affect zebrafish embryogenesis. However, the combination significantly delayed the repair process in comparison to the control (ctrl) or either single MO (mean ± SEM; 2-way ANOVA).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ada WT + MO1-ada2a WT + MO1-ada2b WT + MO1-ada + MO1-ada2b WT + MO1-ada2a + MO1-ada2b
Condition:	ablation: pronephros
Knockdown Reagents:	MO1-ada MO1-ada2a MO1-ada2b
Observed In:	pronephros pronephros regeneration
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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