Fig. 7
- ID
- ZDB-FIG-220727-32
- Publication
- Chen et al., 2022 - Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood-Brain Barrier
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Comprehensive protein corona identification of N4-RMSN50@PEG/THPMP incubated with mouse serum by LC-Ms/MS. (A) SDS-PAGE gel of plasma (control) and corona proteins associated with N4-RMSN50@PEG/THPMP. (B) Classification of corona protein according to (C) molecular weight. and (D) isoelectric point. The most abundant proteins (top 20) are summarized. (E) Heatmap of the most abundant proteins. (F) Venn diagrams report the number of protein corona and the proteins related to BBB transport. (G) Relative abundance (vs mean abundance) of BBB transport associated proteins identified in the protein corona. C: control. N4: N4-RMSN50@PEG/THPMP. |